Apparently in an entire reality where there is no death, there is one being that can kill whomever it pleases.
That beings name….is Thanos.
After a several page long fight between the evil versions of the Defenders and the Guardians ends with the Guardians seemingly killing their foes, they rise again only to be incinerated by Thanos. Thanos who can being permanent death to a world that has none.
Kinda bad ass.