Everything in the Flash status quo changes after this issue; literally everything of importance has changed.
DC Comics Rebirth Spoilers for the The Flash #27 follow.
Eobard Thawn, the Reverse Flash, threatens to continue coming after the Flash – powered by the negative Speed Force right now – leading Iris West to…
…to kill the Reverse Flash!
The Flash in turn, finally, gives in and tries to calm her by finally…
…exposing his secret identity to her!
She is angry at his constant lies to her about his dual persona and just wants him to take her home and leave her, and her injured nephew Wally West, the Kid Flash, alone.
Barry Allen is exposed, lonely and hurt by the end of the issue…
…and presumably still powered by the negative Speed Force.
Wow, how things have changed.